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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 21-30 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395552Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_E10glioblastoma [Pro]
GSE57872GSM1395554Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_E12glioblastoma [Pro]
GSE57872GSM1395555Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F01glioblastoma [Pro]
GSE57872GSM1395557Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F03glioblastoma [Pro]
GSE57872GSM1395561Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F07glioblastoma [Pro]
GSE57872GSM1395817Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C11glioblastoma [Pro]
GSE57872GSM1395563Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F09glioblastoma [Pro]
GSE57872GSM1395566Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F12glioblastoma [Pro]
GSE57872GSM1395823Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D05glioblastoma [Pro]
GSE57872GSM1395568Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G02glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5761-5770 of 5942 results.
Rank orderGene SymbolEnsembl ID
5761ASB15ENSG00000146809
5762KIF4AENSG00000090889
5763PRKAA2ENSG00000162409
5764SERTAD1ENSG00000197019
5765LSSENSG00000160285
5766SGSM3ENSG00000100359
5767SCN9AENSG00000169432
5768SLCO1C1ENSG00000139155
5769PADI2ENSG00000117115
5770C2orf44