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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 21-30 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395578Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G12glioblastoma [Cla]
GSE57872GSM1395838Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E08glioblastoma [Cla]
GSE57872GSM1395842Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E12glioblastoma [Cla]
GSE57872GSM1395843Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F01glioblastoma [Cla]
GSE57872GSM1395845Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F03glioblastoma [Cla]
GSE57872GSM1395853Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F11glioblastoma [Cla]
GSE57872GSM1395862Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G08glioblastoma [Cla]
GSE57872GSM1395864Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G10glioblastoma [Cla]
GSE57872GSM1395865Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G11glioblastoma [Cla]
GSE57872GSM1395869Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H03glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5821-5830 of 5942 results.
Rank orderGene SymbolEnsembl ID
5821LTB4RENSG00000213903
5822DCNENSG00000011465
5823MMP7ENSG00000137673
5824CYR61ENSG00000142871
5825MIR4647
5826TFENSG00000091513
5827FAM59A
5828SH3BGRENSG00000185437
5829ZNF30ENSG00000168661
5830IFT74ENSG00000096872