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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 21-30 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395552Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_E10glioblastoma [Pro]
GSE57872GSM1395554Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_E12glioblastoma [Pro]
GSE57872GSM1395555Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F01glioblastoma [Pro]
GSE57872GSM1395557Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F03glioblastoma [Pro]
GSE57872GSM1395561Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F07glioblastoma [Pro]
GSE57872GSM1395817Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C11glioblastoma [Pro]
GSE57872GSM1395563Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F09glioblastoma [Pro]
GSE57872GSM1395566Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F12glioblastoma [Pro]
GSE57872GSM1395823Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D05glioblastoma [Pro]
GSE57872GSM1395568Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G02glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5841-5850 of 5942 results.
Rank orderGene SymbolEnsembl ID
5841TREM1ENSG00000124731
5842EPHA3ENSG00000044524
5843PAMR1ENSG00000149090
5844FAM182BENSG00000175170
5845SLPIENSG00000124107
5846DEM1
5847RAMP3ENSG00000122679
5848STAMENSG00000136738
5849CNIH3ENSG00000143786
5850FAM198BENSG00000164125