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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 31-40 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395501Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A07glioblastoma [Pro]
GSE57872GSM1395502Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A08glioblastoma [Pro]
GSE57872GSM1395504Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A10glioblastoma [Pro]
GSE57872GSM1395505Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A11glioblastoma [Pro]
GSE57872GSM1395507Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B01glioblastoma [Pro]
GSE57872GSM1395510Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B04glioblastoma [Pro]
GSE57872GSM1395512Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B06glioblastoma [Pro]
GSE57872GSM1395517Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B11glioblastoma [Pro]
GSE57872GSM1395521Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C03glioblastoma [Pro]
GSE57872GSM1395522Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C04glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 161-170 of 5942 results.
Rank orderGene SymbolEnsembl ID
161CHD9ENSG00000177200
162HNRPDL
163PCMTD2ENSG00000203880
164RBMXENSG00000147274
165SPARCL1ENSG00000152583
166PMP2ENSG00000147588
167SF3B1ENSG00000115524
168SSR1ENSG00000124783
169RPS15ENSG00000115268
170ARL4AENSG00000122644