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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 31-40 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395871Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H05glioblastoma [Cla]
GSE57872GSM1395872Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H06glioblastoma [Cla]
GSE57872GSM1395874Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H08glioblastoma [Cla]
GSE57872GSM1395875Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H09glioblastoma [Cla]
GSE57872GSM1395876Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H10glioblastoma [Cla]
GSE57872GSM1395877Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H11glioblastoma [Cla]
GSE57872GSM1395650Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E12glioblastoma [Cla]
GSE57872GSM1395919Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_D05glioblastoma [Cla]
GSE57872GSM1395441Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D07glioblastoma [Cla]
GSE57872GSM1395959Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_G09glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 191-200 of 5942 results.
Rank orderGene SymbolEnsembl ID
191ARF4ENSG00000168374
192LARSENSG00000133706
193HSPD1ENSG00000144381
194COPB2ENSG00000184432
195GPBP1ENSG00000062194
196RBM8AENSG00000265241
197TUBB2BENSG00000137285
198SARSENSG00000031698
199TMEM59ENSG00000116209
200NDUFS2ENSG00000158864