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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 31-40 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395617Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C03glioblastoma [Mes]
GSE57872GSM1395873Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H07glioblastoma [Mes]
GSE57872GSM1395619Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C05glioblastoma [Mes]
GSE57872GSM1395620Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C06glioblastoma [Mes]
GSE57872GSM1395621Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C07glioblastoma [Mes]
GSE57872GSM1395622Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C08glioblastoma [Mes]
GSE57872GSM1395623Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C09glioblastoma [Mes]
GSE57872GSM1395624Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C10glioblastoma [Mes]
GSE57872GSM1395880Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A02glioblastoma [Mes]
GSE57872GSM1395625Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C11glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 301-310 of 5942 results.
Rank orderGene SymbolEnsembl ID
301CYCSENSG00000172115
302ARPC1AENSG00000241685
303DHX9ENSG00000135829
304SERPING1ENSG00000149131
305PSMA2ENSG00000106588
306SUMO2ENSG00000188612
307PLS3ENSG00000102024
308RHBDD2ENSG00000005486
309SS18ENSG00000141380
310CALD1ENSG00000122786