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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 31-40 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395569Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G03glioblastoma [Pro]
GSE57872GSM1395570Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G04glioblastoma [Pro]
GSE57872GSM1395572Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G06glioblastoma [Pro]
GSE57872GSM1395577Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G11glioblastoma [Pro]
GSE57872GSM1395580Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H02glioblastoma [Pro]
GSE57872GSM1395837Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E07glioblastoma [Pro]
GSE57872GSM1395586Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H08glioblastoma [Pro]
GSE57872GSM1395588Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H10glioblastoma [Pro]
GSE57872GSM1395590Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H12glioblastoma [Pro]
GSE57872GSM1395848Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F06glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5741-5750 of 5942 results.
Rank orderGene SymbolEnsembl ID
5741FLRT3ENSG00000125848
5742SLC17A8ENSG00000179520
5743PFKFB3ENSG00000170525
5744ZNF200ENSG00000010539
5745OBFC1ENSG00000107960
5746HEPHENSG00000089472
5747IL6ENSG00000136244
5748PIP5K1AENSG00000143398
5749SLC7A1ENSG00000139514
5750ZNF542