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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 31-40 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395569Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G03glioblastoma [Pro]
GSE57872GSM1395570Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G04glioblastoma [Pro]
GSE57872GSM1395572Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G06glioblastoma [Pro]
GSE57872GSM1395577Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G11glioblastoma [Pro]
GSE57872GSM1395580Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H02glioblastoma [Pro]
GSE57872GSM1395837Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E07glioblastoma [Pro]
GSE57872GSM1395586Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H08glioblastoma [Pro]
GSE57872GSM1395588Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H10glioblastoma [Pro]
GSE57872GSM1395590Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H12glioblastoma [Pro]
GSE57872GSM1395848Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F06glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5831-5840 of 5942 results.
Rank orderGene SymbolEnsembl ID
5831RARRES3ENSG00000133321
5832HECTD3ENSG00000126107
5833SLC24A2ENSG00000155886
5834SPOCK1ENSG00000152377
5835CITED1ENSG00000125931
5836LTB4RENSG00000213903
5837MECOMENSG00000085276
5838NDRG1ENSG00000104419
5839MTL5
5840ZNF502ENSG00000196653