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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 31-40 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395871Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H05glioblastoma [Cla]
GSE57872GSM1395872Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H06glioblastoma [Cla]
GSE57872GSM1395874Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H08glioblastoma [Cla]
GSE57872GSM1395875Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H09glioblastoma [Cla]
GSE57872GSM1395876Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H10glioblastoma [Cla]
GSE57872GSM1395877Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H11glioblastoma [Cla]
GSE57872GSM1395650Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E12glioblastoma [Cla]
GSE57872GSM1395919Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_D05glioblastoma [Cla]
GSE57872GSM1395441Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D07glioblastoma [Cla]
GSE57872GSM1395959Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_G09glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 121-130 of 5942 results.
Rank orderGene SymbolEnsembl ID
121BCLAF1ENSG00000029363
122SETENSG00000119335
123NFIAENSG00000162599
124HMGN2ENSG00000198830
125MAT2AENSG00000168906
126LAMP2ENSG00000005893
127PPP2R1AENSG00000105568
128NEAT1ENSG00000245532
129YWHAEENSG00000108953
130SSR1ENSG00000124783