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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 31-40 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395843Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F01glioblastoma [Cla]
GSE57872GSM1395845Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F03glioblastoma [Cla]
GSE57872GSM1395853Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F11glioblastoma [Cla]
GSE57872GSM1395862Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G08glioblastoma [Cla]
GSE57872GSM1395864Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G10glioblastoma [Cla]
GSE57872GSM1395865Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G11glioblastoma [Cla]
GSE57872GSM1395869Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H03glioblastoma [Cla]
GSE57872GSM1395871Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H05glioblastoma [Cla]
GSE57872GSM1395872Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H06glioblastoma [Cla]
GSE57872GSM1395874Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H08glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5751-5760 of 5942 results.
Rank orderGene SymbolEnsembl ID
5751GBP2ENSG00000162645
5752SERPINB8ENSG00000166401
5753ASS1ENSG00000130707
5754UAP1ENSG00000117143
5755MPPED2ENSG00000066382
5756CECR1ENSG00000093072
5757HLA-DRAENSG00000204287
5758ERBB2ENSG00000141736
5759AKAP7ENSG00000118507
5760GCATENSG00000100116