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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 41-50 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395594Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A04glioblastoma [Pro]
GSE57872GSM1395851Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F09glioblastoma [Pro]
GSE57872GSM1395855Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G01glioblastoma [Pro]
GSE57872GSM1395611Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B09glioblastoma [Pro]
GSE57872GSM1395614Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B12glioblastoma [Pro]
GSE57872GSM1395400Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A02glioblastoma [Pro]
GSE57872GSM1395912Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_C10glioblastoma [Pro]
GSE57872GSM1395658Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F08glioblastoma [Pro]
GSE57872GSM1395915Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_D01glioblastoma [Pro]
GSE57872GSM1395405Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A07glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 181-190 of 5942 results.
Rank orderGene SymbolEnsembl ID
181SARSENSG00000031698
182COPAENSG00000122218
183HSPA9ENSG00000113013
184USP11ENSG00000102226
185HEPN1ENSG00000221932
186NGFRAP1
187HNRNPKENSG00000165119
188OAZ1ENSG00000104904
189ANKRD10ENSG00000088448
190SDCBPENSG00000137575