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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 1-10 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598286Illumina HiSeq 2000Homo sapiensS5zygote (2PN)-bad
GSE65481GSM1598285Illumina HiSeq 2000Homo sapiensS4zygote (2PN)-bad
GSE65481GSM1598284Illumina HiSeq 2000Homo sapiensS3zygote (2PN)-bad
GSE65481GSM1598303Illumina HiSeq 2000Homo sapiensS22zygote (2PN)-bad
GSE65481GSM1598297Illumina HiSeq 2000Homo sapiensS16zygote (2PN)-bad
GSE65481GSM1598295Illumina HiSeq 2000Homo sapiensS14zygote (2PN)-bad
GSE65481GSM1598294Illumina HiSeq 2000Homo sapiensS13zygote (2PN)-bad
GSE65481GSM1598293Illumina HiSeq 2000Homo sapiensS12zygote (2PN)-bad
GSE65481GSM1598292Illumina HiSeq 2000Homo sapiensS11zygote (2PN)-bad
GSE65481GSM1598291Illumina HiSeq 2000Homo sapiensS10zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 291-300 of 19195 results.
Rank orderGene SymbolEnsembl ID
291SMC4ENSG00000113810
292PPP2R5CENSG00000078304
293PLEK2ENSG00000100558
294RPA1ENSG00000132383
295METTL9ENSG00000197006
296CNOT7ENSG00000198791
297STK24ENSG00000102572
298GMFBENSG00000197045
299ARIH1ENSG00000166233
300TBC1D23ENSG00000036054