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  glioblastoma [Pro+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Cla]

Displaying 1-10 of 20 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395508Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B02glioblastoma [Pro+Cla]
GSE57872GSM1395511Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B05glioblastoma [Pro+Cla]
GSE57872GSM1395516Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B10glioblastoma [Pro+Cla]
GSE57872GSM1395531Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D01glioblastoma [Pro+Cla]
GSE57872GSM1395807Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C01glioblastoma [Pro+Cla]
GSE57872GSM1395564Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F10glioblastoma [Pro+Cla]
GSE57872GSM1395825Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D07glioblastoma [Pro+Cla]
GSE57872GSM1395835Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E05glioblastoma [Pro+Cla]
GSE57872GSM1395581Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H03glioblastoma [Pro+Cla]
GSE57872GSM1395854Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F12glioblastoma [Pro+Cla]

Gene rank in glioblastoma [Pro+Cla]

Displaying 5851-5860 of 5942 results.
Rank orderGene SymbolEnsembl ID
5851PTPDC1ENSG00000158079
5852CD83ENSG00000112149
5853KITLGENSG00000049130
5854NLRC5ENSG00000140853
5855ZNF30ENSG00000168661
5856RGP1ENSG00000107185
5857CDH19ENSG00000071991
5858KIF4AENSG00000090889
5859SLC9A6ENSG00000198689
5860PTGESENSG00000148344