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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 1-10 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395507Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B01glioblastoma [Pro]
GSE57872GSM1395510Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B04glioblastoma [Pro]
GSE57872GSM1395512Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B06glioblastoma [Pro]
GSE57872GSM1395517Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B11glioblastoma [Pro]
GSE57872GSM1395521Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C03glioblastoma [Pro]
GSE57872GSM1395522Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C04glioblastoma [Pro]
GSE57872GSM1395523Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C05glioblastoma [Pro]
GSE57872GSM1395530Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C12glioblastoma [Pro]
GSE57872GSM1395532Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D02glioblastoma [Pro]
GSE57872GSM1395533Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D03glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 151-160 of 5942 results.
Rank orderGene SymbolEnsembl ID
151IL1RAPENSG00000196083
152MARCKSENSG00000277443
153SLC25A5ENSG00000005022
154HSPD1ENSG00000144381
155RBM39ENSG00000131051
156SETENSG00000119335
157IDH1ENSG00000138413
158ORC4ENSG00000115947
159VCANENSG00000038427
160EGR1ENSG00000120738