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  glioblastoma [Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu]

Displaying 1-10 of 24 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395764Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G06glioblastoma [Neu]
GSE57872GSM1395771Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H01glioblastoma [Neu]
GSE57872GSM1395772Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H02glioblastoma [Neu]
GSE57872GSM1395774Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H04glioblastoma [Neu]
GSE57872GSM1395776Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H06glioblastoma [Neu]
GSE57872GSM1395777Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H07glioblastoma [Neu]
GSE57872GSM1395778Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H08glioblastoma [Neu]
GSE57872GSM1395804Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B10glioblastoma [Neu]
GSE57872GSM1395886Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A08glioblastoma [Neu]
GSE57872GSM1395900Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_B10glioblastoma [Neu]

Gene rank in glioblastoma [Neu]

Displaying 5791-5800 of 5942 results.
Rank orderGene SymbolEnsembl ID
5791RNASE1ENSG00000129538
5792HSF5ENSG00000176160
5793ZNF830ENSG00000198783
5794RFWD3ENSG00000168411
5795DHCR7ENSG00000172893
5796ECSITENSG00000130159
5797NID2ENSG00000087303
5798SMYD5ENSG00000135632
5799TIMM17BENSG00000126768
5800CCNB1ENSG00000134057