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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 1-10 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395507Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B01glioblastoma [Pro]
GSE57872GSM1395510Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B04glioblastoma [Pro]
GSE57872GSM1395512Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B06glioblastoma [Pro]
GSE57872GSM1395517Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B11glioblastoma [Pro]
GSE57872GSM1395521Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C03glioblastoma [Pro]
GSE57872GSM1395522Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C04glioblastoma [Pro]
GSE57872GSM1395523Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C05glioblastoma [Pro]
GSE57872GSM1395530Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C12glioblastoma [Pro]
GSE57872GSM1395532Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D02glioblastoma [Pro]
GSE57872GSM1395533Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D03glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5791-5800 of 5942 results.
Rank orderGene SymbolEnsembl ID
5791ZC4H2ENSG00000126970
5792GPNMBENSG00000136235
5793CD83ENSG00000112149
5794OGG1ENSG00000114026
5795TEX261ENSG00000144043
5796S1PR1ENSG00000170989
5797PUS3ENSG00000110060
5798PLA2G5ENSG00000127472
5799SRPX2ENSG00000102359
5800ZNF132ENSG00000131849