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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 1-10 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395507Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B01glioblastoma [Pro]
GSE57872GSM1395510Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B04glioblastoma [Pro]
GSE57872GSM1395512Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B06glioblastoma [Pro]
GSE57872GSM1395517Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B11glioblastoma [Pro]
GSE57872GSM1395521Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C03glioblastoma [Pro]
GSE57872GSM1395522Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C04glioblastoma [Pro]
GSE57872GSM1395523Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C05glioblastoma [Pro]
GSE57872GSM1395530Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C12glioblastoma [Pro]
GSE57872GSM1395532Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D02glioblastoma [Pro]
GSE57872GSM1395533Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D03glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5811-5820 of 5942 results.
Rank orderGene SymbolEnsembl ID
5811SH3BGRENSG00000185437
5812GBP2ENSG00000162645
5813COL14A1ENSG00000187955
5814TTC21AENSG00000168026
5815C6orf228
5816HSPBAP1ENSG00000169087
5817TPPP3ENSG00000159713
5818VCAM1ENSG00000162692
5819TFCP2L1ENSG00000115112
5820GOLGA6CENSG00000167195