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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 1-10 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395507Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B01glioblastoma [Pro]
GSE57872GSM1395510Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B04glioblastoma [Pro]
GSE57872GSM1395512Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B06glioblastoma [Pro]
GSE57872GSM1395517Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B11glioblastoma [Pro]
GSE57872GSM1395521Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C03glioblastoma [Pro]
GSE57872GSM1395522Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C04glioblastoma [Pro]
GSE57872GSM1395523Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C05glioblastoma [Pro]
GSE57872GSM1395530Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C12glioblastoma [Pro]
GSE57872GSM1395532Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D02glioblastoma [Pro]
GSE57872GSM1395533Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D03glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5861-5870 of 5942 results.
Rank orderGene SymbolEnsembl ID
5861HLA-DRAENSG00000204287
5862UNC13BENSG00000198722
5863SPOCK3ENSG00000196104
5864FANCBENSG00000181544
5865MTM1ENSG00000171100
5866ICAM1ENSG00000090339
5867AURKBENSG00000178999
5868ERBB2ENSG00000141736
5869IL8
5870SERPINI1ENSG00000163536