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  glioblastoma [Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu]

Displaying 1-10 of 24 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395764Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G06glioblastoma [Neu]
GSE57872GSM1395771Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H01glioblastoma [Neu]
GSE57872GSM1395772Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H02glioblastoma [Neu]
GSE57872GSM1395774Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H04glioblastoma [Neu]
GSE57872GSM1395776Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H06glioblastoma [Neu]
GSE57872GSM1395777Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H07glioblastoma [Neu]
GSE57872GSM1395778Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H08glioblastoma [Neu]
GSE57872GSM1395804Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B10glioblastoma [Neu]
GSE57872GSM1395886Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A08glioblastoma [Neu]
GSE57872GSM1395900Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_B10glioblastoma [Neu]

Gene rank in glioblastoma [Neu]

Displaying 5871-5880 of 5942 results.
Rank orderGene SymbolEnsembl ID
5871USP44ENSG00000136014
5872ZNF691ENSG00000164011
5873TMCC3ENSG00000057704
5874NANPENSG00000170191
5875C9orf16ENSG00000171159
5876KITLGENSG00000049130
5877BCORENSG00000183337
5878SPRY4ENSG00000187678
5879C21orf7
5880GCNT2ENSG00000111846