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  glioblastoma [Cla+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla+Mes]

Displaying 1-6 of 6 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395850Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F08glioblastoma [Cla+Mes]
GSE57872GSM1395682Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_H08glioblastoma [Cla+Mes]
GSE57872GSM1395645Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E07glioblastoma [Cla+Mes]
GSE57872GSM1395627Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D01glioblastoma [Cla+Mes]
GSE57872GSM1395618Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C04glioblastoma [Cla+Mes]
GSE57872GSM1395599Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A09glioblastoma [Cla+Mes]

Gene rank in glioblastoma [Cla+Mes]

Displaying 5841-5850 of 5942 results.
Rank orderGene SymbolEnsembl ID
5841RPE65ENSG00000116745
5842RPRD1AENSG00000141425
5843RPS4Y1ENSG00000129824
5844RRM2ENSG00000171848
5845RWDD3ENSG00000122481
5846SAA1ENSG00000173432
5847SEPT8ENSG00000164402
5848SERPINA1ENSG00000197249
5849SERPINA3ENSG00000196136
5850SFRP4ENSG00000106483