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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 1-10 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395526Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C08glioblastoma [Cla]
GSE57872GSM1395783Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A01glioblastoma [Cla]
GSE57872GSM1395788Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A06glioblastoma [Cla]
GSE57872GSM1395789Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A07glioblastoma [Cla]
GSE57872GSM1395791Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A09glioblastoma [Cla]
GSE57872GSM1395799Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B05glioblastoma [Cla]
GSE57872GSM1395800Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B06glioblastoma [Cla]
GSE57872GSM1395802Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B08glioblastoma [Cla]
GSE57872GSM1395811Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C05glioblastoma [Cla]
GSE57872GSM1395813Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C07glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 181-190 of 5942 results.
Rank orderGene SymbolEnsembl ID
181RASSF2ENSG00000101265
182CSDE1ENSG00000009307
183CD9ENSG00000010278
184HNRNPH1ENSG00000169045
185TBL1XR1ENSG00000177565
186ARF1ENSG00000143761
187RPS19ENSG00000105372
188G3BP1ENSG00000145907
189LIMA1ENSG00000050405
190IPO9ENSG00000198700