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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 1-10 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395526Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C08glioblastoma [Cla]
GSE57872GSM1395783Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A01glioblastoma [Cla]
GSE57872GSM1395788Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A06glioblastoma [Cla]
GSE57872GSM1395789Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A07glioblastoma [Cla]
GSE57872GSM1395791Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A09glioblastoma [Cla]
GSE57872GSM1395799Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B05glioblastoma [Cla]
GSE57872GSM1395800Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B06glioblastoma [Cla]
GSE57872GSM1395802Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B08glioblastoma [Cla]
GSE57872GSM1395811Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C05glioblastoma [Cla]
GSE57872GSM1395813Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C07glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 221-230 of 5942 results.
Rank orderGene SymbolEnsembl ID
221RPL21ENSG00000122026
222RPN1ENSG00000163902
223PPIBENSG00000166794
224PARK7ENSG00000116288
225ORC4ENSG00000115947
226MEG3ENSG00000214548
227TAX1BP1ENSG00000106052
228ALDOCENSG00000109107
229EGR1ENSG00000120738
230ZKSCAN1ENSG00000106261