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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 1-10 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395762Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G04glioblastoma [Mes]
GSE57872GSM1395765Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G07glioblastoma [Mes]
GSE57872GSM1395766Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G08glioblastoma [Mes]
GSE57872GSM1395767Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G09glioblastoma [Mes]
GSE57872GSM1395769Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G11glioblastoma [Mes]
GSE57872GSM1395775Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H05glioblastoma [Mes]
GSE57872GSM1395780Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H10glioblastoma [Mes]
GSE57872GSM1395782Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H12glioblastoma [Mes]
GSE57872GSM1395814Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C08glioblastoma [Mes]
GSE57872GSM1395826Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D08glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 5671-5680 of 5942 results.
Rank orderGene SymbolEnsembl ID
5671CBSENSG00000160200
5672NBEAENSG00000172915
5673TGIF2ENSG00000118707
5674SNRKENSG00000163788
5675ZFP1ENSG00000184517
5676RBM17ENSG00000134453
5677ST3GAL5ENSG00000115525
5678ZNF224ENSG00000267680
5679TPP2ENSG00000134900
5680SNHG11ENSG00000174365