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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 1-10 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395616Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C02glioblastoma [Neu+Mes]
GSE57872GSM1395638Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D12glioblastoma [Neu+Mes]
GSE57872GSM1395642Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E04glioblastoma [Neu+Mes]
GSE57872GSM1395651Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F01glioblastoma [Neu+Mes]
GSE57872GSM1395662Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F12glioblastoma [Neu+Mes]
GSE57872GSM1395672Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G10glioblastoma [Neu+Mes]
GSE57872GSM1395686Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_H12glioblastoma [Neu+Mes]
GSE57872GSM1395687Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A01glioblastoma [Neu+Mes]
GSE57872GSM1395693Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A07glioblastoma [Neu+Mes]
GSE57872GSM1395694Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A08glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 5861-5870 of 5942 results.
Rank orderGene SymbolEnsembl ID
5861NDNFENSG00000173376
5862RAD18ENSG00000070950
5863NUSAP1ENSG00000137804
5864KIF15ENSG00000163808
5865KIF20AENSG00000112984
5866C1orf87ENSG00000162598
5867TNRENSG00000116147
5868BRD1ENSG00000100425
5869FAM171A1ENSG00000148468
5870CHRNA1ENSG00000138435