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  zygote (2PN)-good

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-good

Displaying 1-10 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598283Illumina HiSeq 2000Homo sapiensS2zygote (2PN)-good
GSE65481GSM1598287Illumina HiSeq 2000Homo sapiensS6zygote (2PN)-good
GSE65481GSM1598288Illumina HiSeq 2000Homo sapiensS7zygote (2PN)-good
GSE65481GSM1598289Illumina HiSeq 2000Homo sapiensS8zygote (2PN)-good
GSE65481GSM1598290Illumina HiSeq 2000Homo sapiensS9zygote (2PN)-good
GSE65481GSM1598296Illumina HiSeq 2000Homo sapiensS15zygote (2PN)-good
GSE65481GSM1598298Illumina HiSeq 2000Homo sapiensS17zygote (2PN)-good
GSE65481GSM1598299Illumina HiSeq 2000Homo sapiensS18zygote (2PN)-good
GSE65481GSM1598300Illumina HiSeq 2000Homo sapiensS19zygote (2PN)-good
GSE65481GSM1598301Illumina HiSeq 2000Homo sapiensS20zygote (2PN)-good

Gene rank in zygote (2PN)-good

Displaying 1-10 of 19195 results.
Rank orderGene SymbolEnsembl ID
1PTTG1ENSG00000164611
2FTLENSG00000087086
3WEE2ENSG00000214102
4RGS2ENSG00000116741
5DLGAP5ENSG00000126787
6PLAC1L
7DPPA5ENSG00000203909
8DNMT1ENSG00000130816
9DPPA3ENSG00000187569
10H3F3BENSG00000132475