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Gene View

General Information

ATIC[ENSG00000138363]

SynonymsAICAR;AICARFT;HEL-S-70p;IMPCHASE;PURH
Description5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Chromosome2q35
Database ReferenceMIM:601731 HGNC:794 HPRD:03434 Vega:OTTHUMG00000133023 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
ATIC expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC002,340
candidate PCa CTC CSPC01.520
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)0014,130
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)016,380
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)02.573
PCa cell line01,275.53,046
white blood cell CRPC000
white blood cell healthy00229
Displaying 1-20 of 28 results.
Comparing ATIC expression between groupsFDR
PCa cell line VS white blood cell CRPCNS
PCa cell line VS white blood cell healthy6.13727155302206e-05
candidate PCa CTC CRPC VS PCa cell line0.00909731205821082
candidate PCa CTC CRPC VS candidate PCa CTC CSPCNS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthyNS
candidate PCa CTC CSPC VS PCa cell line6.15991771306992e-16
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)0.0227976605906502
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)0.0129114339325331
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell lineNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPCNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthyNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for ATIC

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others