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General Information

C3[ENSG00000125730]

SynonymsAHUS5;ARMD9;ASP;C3a;C3b;CPAMD1;HEL-S-62p
Descriptioncomplement component 3
Chromosome19p13.3-p13.2
Database ReferenceMIM:120700 HGNC:1318 HPRD:00400 Vega:OTTHUMG00000150335 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
C3 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell0068.767
CAF087.6496,556.587
Endothelial cell0039.12
Macrophage002,221.392
melanoma00631.199
melanoma tumor00846.096
T-cell00380.649
unresolved002,183.21
Displaying 1-20 of 28 results.
Comparing C3 expression between groupsFDR
B-cell VS CAF4.69199761672569e-20
B-cell VS Endothelial cell2.60887511931377e-26
B-cell VS Macrophage1.323814856317e-17
B-cell VS T-cell1.86056250290587e-30
B-cell VS melanoma tumor5.70290248288146e-11
B-cell VS melanoma1.20366674588884e-73
B-cell VS unresolved1.44197800484173e-26
CAF VS Endothelial cell9.02752321220659e-09
CAF VS Macrophage3.0657633403279e-05
CAF VS T-cell8.46718791978959e-21
CAF VS melanoma tumor8.94798138501242e-10
CAF VS melanoma2.22854950767312e-25
CAF VS unresolved9.12755453719664e-05
Endothelial cell VS Macrophage7.71443443585098e-06
Endothelial cell VS T-cell3.1310167957036e-12
Endothelial cell VS melanoma tumor1.63337490518563e-09
Endothelial cell VS melanoma2.50121626703905e-42
Endothelial cell VS unresolved1.8102616803699e-06
Macrophage VS T-cell2.83657661577156e-11
Macrophage VS melanoma tumor5.76736880184152e-18
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for C3

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]