gene,0,0 GSM1643170,0,83.976 GSM1643171,0,90.242 GSM1643147,0,46.66 GSM1643148,0,54.367 GSM1643172,0,67.518 GSM1643173,0,94.911 GSM1643174,0,135.86 GSM1643175,0,69.439 GSM1643176,0,59.022 GSM1643149,0,63.502 GSM1643150,0,71.119 GSM1643177,0,140.182 GSM1643178,0,175.831 GSM1643179,0,185.421 GSM1643151,0,106.185 GSM1643152,0,78.925 GSM1643157,0,66.833 GSM1643158,0,82.614 GSM1643163,0,79.928 GSM1643164,0,79.11 GSM1643153,0,146.935 GSM1643154,0,106.132 GSM1643143,0,27.568 GSM1643144,0,23.575 GSM1643155,0,34.172 GSM1643156,0,31.075 GSM1643159,0,28.427 GSM1643160,0,30.385 GSM1643165,0,31.736 GSM1643166,0,27.498 GSM1643167,0,32.582 GSM1643168,0,34.286 GSM1643169,0,25.846 GSM1643145,0,32.425 GSM1643146,0,28.115 GSM1643161,0,28.608 GSM1643162,0,29.754
| Synonyms | HEL-S-98n |
| Description | catechol-O-methyltransferase |
|---|---|
| Chromosome | 22q11.21 |
| Database Reference | MIM:116790 HGNC:2228 HPRD:00284 Vega:OTTHUMG00000150529 |
| See related | THE HUMAN PROTEIN ATLAS |
| Dataset | GSE67259 |
| COMT expression in each cell group | Minimum Value (TPM) | Median Value (TPM) | Maximum Value (TPM) |
|---|---|---|---|
| d2 AG+ cells | 83.976 | 87.109 | 90.242 |
| d2 BTAG+ cells | 46.66 | 67.518 | 135.86 |
| d4 AG+ cells | 59.022 | 64.231 | 69.439 |
| d4 BTAG+ cells | 63.502 | 140.182 | 185.421 |
| d6 BTAG+ cells | 66.833 | 80.769 | 106.185 |
| d6 CSM+ cells | 79.11 | 79.519 | 79.928 |
| d8 BTAG+ cells | 106.132 | 126.534 | 146.935 |
| hiPSC | 23.575 | 30.385 | 34.286 |
| iMeLC | 28.115 | 29.181 | 32.425 |
| Comparing COMT expression between groups | FDR |
|---|---|
| d4 AG+ cells VS iMeLC | 0.0108101277479452 |
| d4 BTAG+ cells VS d6 BTAG+ cells | NS |
| d4 BTAG+ cells VS d6 CSM+ cells | NS |
| d4 BTAG+ cells VS d8 BTAG+ cells | NS |
| d4 BTAG+ cells VS hiPSC | 2.00156780356163e-06 |
| d4 BTAG+ cells VS iMeLC | 0.00790302433840666 |
| d6 BTAG+ cells VS d6 CSM+ cells | NS |
| d6 BTAG+ cells VS d8 BTAG+ cells | NS |
| d6 BTAG+ cells VS hiPSC | 2.39256543688133e-07 |
| d6 BTAG+ cells VS iMeLC | 0.00341648709421218 |
| d6 CSM+ cells VS d8 BTAG+ cells | NS |
| d6 CSM+ cells VS hiPSC | 3.36519996047185e-07 |
| d6 CSM+ cells VS iMeLC | 0.00420395597829771 |
| d8 BTAG+ cells VS hiPSC | 1.7729491269782e-07 |
| d8 BTAG+ cells VS iMeLC | 0.0112438459169354 |
| hiPSC VS iMeLC | NS |
Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.
KEGG GO Others d2 AG+ cells[2]
d2 BTAG+ cells[5]
d4 AG+ cells[2]
d4 BTAG+ cells[5]
d6 BTAG+ cells[4]
d6 CSM+ cells[2]
d8 BTAG+ cells[2]
hiPSC[11]
iMeLC[4]
