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Gene View

General Information

COMT[ENSG00000093010]

SynonymsHEL-S-98n
Descriptioncatechol-O-methyltransferase
Chromosome22q11.21
Database ReferenceMIM:116790 HGNC:2228 HPRD:00284 Vega:OTTHUMG00000150529 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE75140

Gene Rank

Gene Expression

 

Displaying 1-9 of 9 results.
COMT expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
ESC H9[53 days]0061.965
fetal human cortex 1[12 weeks post-conception]00864.005
fetal human cortex 2[13 weeks post-conception]00740.128
iPSC 409B2[33 days]00214.878
iPSC 409B2[35 days]00378.365
iPSC 409B2[37 days]00372.403
iPSC 409B2[41 days]00868.597
iPSC 409B2[58 days]00527.546
iPSC 409B2[65 days]00395.782
Displaying 1-20 of 36 results.
Comparing COMT expression between groupsFDR
ESC H9[53 days] VS fetal human cortex 1[12 weeks post-conception]4.29675950070459e-08
ESC H9[53 days] VS fetal human cortex 2[13 weeks post-conception]0.00475240653278436
ESC H9[53 days] VS iPSC 409B2[33 days]NS
ESC H9[53 days] VS iPSC 409B2[35 days]0.00755300725596171
ESC H9[53 days] VS iPSC 409B2[37 days]0.00833018721451556
ESC H9[53 days] VS iPSC 409B2[41 days]0.000719011559766608
ESC H9[53 days] VS iPSC 409B2[58 days]NS
ESC H9[53 days] VS iPSC 409B2[65 days]NS
fetal human cortex 1[12 weeks post-conception] VS fetal human cortex 2[13 weeks post-conception]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[33 days]2.82394241349488e-05
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[35 days]0.0169296881365919
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[37 days]0.00875155189156548
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[41 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[58 days]0.000288698103536445
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[65 days]0.000130705359593153
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[33 days]0.0303160611565706
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[35 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[37 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[41 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[58 days]NS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for COMT

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 ESC H9[53 days][96]
 fetal human cortex 1[12 weeks post-conception][164]
 fetal human cortex 2[13 weeks post-conception][62]
 iPSC 409B2[33 days][40]
 iPSC 409B2[35 days][68]
 iPSC 409B2[37 days][71]
 iPSC 409B2[41 days][74]
 iPSC 409B2[58 days][79]
 iPSC 409B2[65 days][80]