Gene View

General Information

DSTN[ENSG00000125868]

SynonymsACTDP;ADF;HEL32;bA462D18.2
Descriptiondestrin, actin depolymerizing factor
Chromosome20p12.1
Database ReferenceMIM:609114 HGNC:15750 HPRD:16446 Vega:OTTHUMG00000031947 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Created with Highcharts 4.2.5RankRank of DSTN Expression in GSE67980lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)lineage-confirmed PCa CTC CRPC progressed on enzalutamide(Group B)lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)PCa cell linecandidate PCa CTC CRPCcandidate PCa CTC CSPCwhite blood cell CRPCwhite blood cell healthy0102030405060708090100

Gene Expression

Created with Highcharts 4.2.5

 

Displaying 1-8 of 8 results.
DSTN expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC057,764
candidate PCa CTC CSPC1166,643
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)141419,989
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)081119,163
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)104,40310,236
PCa cell line102,5527,376
white blood cell CRPC24.57
white blood cell healthy225
Created with Highcharts 4.2.5Cell GroupGene Expression Level (Read count)DSTN Expression in Each Cell Groupcandidate PCa CTCCRPCcandidate PCa CTC CRPCcandidate PCa CTCCSPCcandidate PCa CTC CSPClineage-confirmed PCaCTC CRPCenzalutamide-naive(Group A)lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)lineage-confirmed PCaCTC CRPC progressedon enzalutamide (GroupB)lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)lineage-confirmed PCaCTC CSPCenzalutamide-naive(Group A)lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)PCa cell linewhite blood cell CRPCwhite blood cell healthy-5k0k5k10k15k20k25k
Displaying 1-20 of 28 results.
Comparing DSTN expression between groupsFDR
PCa cell line VS white blood cell CRPC9.74904755931496e-09
PCa cell line VS white blood cell healthy2.01166966147858e-10
candidate PCa CTC CRPC VS PCa cell line0.0243067294811699
candidate PCa CTC CRPC VS candidate PCa CTC CSPCNS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)0.0383726867840163
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)0.0293735689953605
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthyNS
candidate PCa CTC CSPC VS PCa cell line0.0365006264628019
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell lineNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPC0.00279446815760559
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthy3.06470111475252e-05
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for DSTN

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others