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General Information

GPX4[ENSG00000167468]

SynonymsGPx-4;GSHPx-4;MCSP;PHGPx;SMDS;snGPx;snPHGPx
Descriptionglutathione peroxidase 4
Chromosome19p13.3
Database ReferenceMIM:138322 HGNC:4556 HPRD:11819 Vega:OTTHUMG00000181874 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
GPX4 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell001,336.808
CAF0449.4071,725.732
Endothelial cell073.315639.204
Macrophage0307.1751,957.064
melanoma0317.8812,401.856
melanoma tumor033.9544,565.863
T-cell002,434.507
unresolved0183.5282,290.973
Displaying 1-20 of 28 results.
Comparing GPX4 expression between groupsFDR
B-cell VS CAF0.000720140239415908
B-cell VS Endothelial cellNS
B-cell VS Macrophage0.00643598985244766
B-cell VS T-cellNS
B-cell VS melanoma tumorNS
B-cell VS melanoma1.834916504282e-17
B-cell VS unresolvedNS
CAF VS Endothelial cell3.03003178149389e-06
CAF VS MacrophageNS
CAF VS T-cell0.00513369693705103
CAF VS melanoma tumorNS
CAF VS melanoma0.0221446606292553
CAF VS unresolvedNS
Endothelial cell VS Macrophage2.28590073675165e-05
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumorNS
Endothelial cell VS melanoma2.55719360957895e-12
Endothelial cell VS unresolved0.00745646455501895
Macrophage VS T-cell0.0251026496019963
Macrophage VS melanoma tumorNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for GPX4

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]