gene,0,0 GSM1643170,0,176.311 GSM1643171,0,98.562 GSM1643147,0,39.994 GSM1643148,0,42.286 GSM1643172,0,85.221 GSM1643173,0,62.919 GSM1643174,0,198.053 GSM1643175,0,113.628 GSM1643176,0,113.871 GSM1643149,0,95.388 GSM1643150,0,81.711 GSM1643177,0,148.39 GSM1643178,0,260.971 GSM1643179,0,330.649 GSM1643151,0,215.833 GSM1643152,0,154.871 GSM1643157,0,70.175 GSM1643158,0,87.244 GSM1643163,0,93.481 GSM1643164,0,91.367 GSM1643153,0,271.229 GSM1643154,0,195.096 GSM1643143,0,26.457 GSM1643144,0,26.522 GSM1643155,0,20.734 GSM1643156,0,18.757 GSM1643159,0,27.125 GSM1643160,0,13.973 GSM1643165,0,14.425 GSM1643166,0,16.866 GSM1643167,0,18.443 GSM1643168,0,13.545 GSM1643169,0,25.272 GSM1643145,0,11.224 GSM1643146,0,17.405 GSM1643161,0,9.676 GSM1643162,0,6.897
| Synonyms | DRB1;DRw10;HLA-DR1B;HLA-DRB;SS1 |
| Description | major histocompatibility complex, class II, DR beta 1 |
|---|---|
| Chromosome | 6p21.3 |
| Database Reference | MIM:142857 HGNC:4948 HPRD:08349 Vega:OTTHUMG00000031196 |
| See related | THE HUMAN PROTEIN ATLAS |
| Dataset | GSE67259 |
| HLA-DRB1 expression in each cell group | Minimum Value (TPM) | Median Value (TPM) | Maximum Value (TPM) |
|---|---|---|---|
| d2 AG+ cells | 98.562 | 137.436 | 176.311 |
| d2 BTAG+ cells | 39.994 | 62.919 | 198.053 |
| d4 AG+ cells | 113.628 | 113.75 | 113.871 |
| d4 BTAG+ cells | 81.711 | 148.39 | 330.649 |
| d6 BTAG+ cells | 70.175 | 121.058 | 215.833 |
| d6 CSM+ cells | 91.367 | 92.424 | 93.481 |
| d8 BTAG+ cells | 195.096 | 233.163 | 271.229 |
| hiPSC | 13.545 | 18.757 | 27.125 |
| iMeLC | 6.897 | 10.45 | 17.405 |
| Comparing HLA-DRB1 expression between groups | FDR |
|---|---|
| d4 AG+ cells VS iMeLC | 0.00889752365592611 |
| d4 BTAG+ cells VS d6 BTAG+ cells | NS |
| d4 BTAG+ cells VS d6 CSM+ cells | NS |
| d4 BTAG+ cells VS d8 BTAG+ cells | NS |
| d4 BTAG+ cells VS hiPSC | 1.23493280640122e-06 |
| d4 BTAG+ cells VS iMeLC | 0.00279884079526929 |
| d6 BTAG+ cells VS d6 CSM+ cells | NS |
| d6 BTAG+ cells VS d8 BTAG+ cells | NS |
| d6 BTAG+ cells VS hiPSC | 4.2654552576942e-06 |
| d6 BTAG+ cells VS iMeLC | 0.00535309048091731 |
| d6 CSM+ cells VS d8 BTAG+ cells | NS |
| d6 CSM+ cells VS hiPSC | 2.54410237176396e-06 |
| d6 CSM+ cells VS iMeLC | 0.0131763604092926 |
| d8 BTAG+ cells VS hiPSC | 1.80482083710729e-07 |
| d8 BTAG+ cells VS iMeLC | 0.0104253762863902 |
| hiPSC VS iMeLC | NS |
Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.
KEGG GO Others d2 AG+ cells[2]
d2 BTAG+ cells[5]
d4 AG+ cells[2]
d4 BTAG+ cells[5]
d6 BTAG+ cells[4]
d6 CSM+ cells[2]
d8 BTAG+ cells[2]
hiPSC[11]
iMeLC[4]
