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General Information

HLA-E[ENSG00000204592]

SynonymsEA1.2;EA2.1;HLA-6.2;MHC;QA1
Descriptionmajor histocompatibility complex, class I, E
Chromosome6p21.3
Database ReferenceMIM:143010 HGNC:4962 HPRD:00877 Vega:OTTHUMG00000031155 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
HLA-E expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell01,541.4986,751.971
CAF0274.2522,417.286
Endothelial cell534.9682,315.3118,637.864
Macrophage16.481,427.2884,216.15
melanoma0366.5065,341.131
melanoma tumor01,443.8166,970.565
T-cell02,129.3079,195.805
unresolved0348.5534,400.811
Displaying 1-20 of 28 results.
Comparing HLA-E expression between groupsFDR
B-cell VS CAF4.10689643129165e-25
B-cell VS Endothelial cell0.0127280876575434
B-cell VS MacrophageNS
B-cell VS T-cell7.51691236096436e-13
B-cell VS melanoma tumorNS
B-cell VS melanoma1.06435164267242e-62
B-cell VS unresolved5.04652766271139e-14
CAF VS Endothelial cell1.36717409507297e-11
CAF VS Macrophage3.01760918889221e-09
CAF VS T-cell8.53644220501734e-56
CAF VS melanoma tumor1.45383323020521e-15
CAF VS melanomaNS
CAF VS unresolvedNS
Endothelial cell VS MacrophageNS
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumor0.0396813559711826
Endothelial cell VS melanoma2.75192518284048e-16
Endothelial cell VS unresolved6.28864901476548e-06
Macrophage VS T-cell0.0394226343868731
Macrophage VS melanoma tumorNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HLA-E

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]