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Gene View

General Information

HLCS[ENSG00000159267]

SynonymsHCS
Descriptionholocarboxylase synthetase
Chromosome21q22.13
Database ReferenceMIM:609018 HGNC:4976 HPRD:08360 Vega:OTTHUMG00000086636 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
HLCS expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC0032
candidate PCa CTC CSPC00618
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)0151,387
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)011,991
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)00.5211
PCa cell line01152,025
white blood cell CRPC555
white blood cell healthy003
Displaying 1-20 of 28 results.
Comparing HLCS expression between groupsFDR
PCa cell line VS white blood cell CRPC0.0066797727054694
PCa cell line VS white blood cell healthy7.39151719345351e-05
candidate PCa CTC CRPC VS PCa cell line5.17856340516515e-11
candidate PCa CTC CRPC VS candidate PCa CTC CSPC0.0237953648092185
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)2.02930383755039e-05
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthyNS
candidate PCa CTC CSPC VS PCa cell line0.0348024831027667
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell lineNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPCNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthyNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HLCS

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others