gene,0,0 GSM1643170,0,59.277 GSM1643171,0,50.881 GSM1643147,0,50.315 GSM1643148,0,57.388 GSM1643172,0,41.17 GSM1643173,0,88.512 GSM1643174,0,60.08 GSM1643175,0,50.817 GSM1643176,0,66.176 GSM1643149,0,108.899 GSM1643150,0,134.672 GSM1643177,0,92.251 GSM1643178,0,95.628 GSM1643179,0,113.342 GSM1643151,0,91.181 GSM1643152,0,93.816 GSM1643157,0,87.472 GSM1643158,0,100.16 GSM1643163,0,78.017 GSM1643164,0,71.063 GSM1643153,0,85.25 GSM1643154,0,96.768 GSM1643143,0,260.565 GSM1643144,0,281.425 GSM1643155,0,247.843 GSM1643156,0,219.202 GSM1643159,0,185.104 GSM1643160,0,213.582 GSM1643165,0,169.395 GSM1643166,0,149.225 GSM1643167,0,142.316 GSM1643168,0,159.576 GSM1643169,0,201.312 GSM1643145,0,163.681 GSM1643146,0,231.615 GSM1643161,0,135.89 GSM1643162,0,170.048
| Synonyms | HMGCS |
| Description | 3-hydroxy-3-methylglutaryl-CoA synthase 1 |
|---|---|
| Chromosome | 5p12 |
| Database Reference | MIM:142940 HGNC:5007 HPRD:07515 Vega:OTTHUMG00000162231 |
| See related | THE HUMAN PROTEIN ATLAS |
| Dataset | GSE67259 |
| HMGCS1 expression in each cell group | Minimum Value (TPM) | Median Value (TPM) | Maximum Value (TPM) |
|---|---|---|---|
| d2 AG+ cells | 50.881 | 55.079 | 59.277 |
| d2 BTAG+ cells | 41.17 | 57.388 | 88.512 |
| d4 AG+ cells | 50.817 | 58.496 | 66.176 |
| d4 BTAG+ cells | 92.251 | 108.899 | 134.672 |
| d6 BTAG+ cells | 87.472 | 92.498 | 100.16 |
| d6 CSM+ cells | 71.063 | 74.54 | 78.017 |
| d8 BTAG+ cells | 85.25 | 91.009 | 96.768 |
| hiPSC | 142.316 | 201.312 | 281.425 |
| iMeLC | 135.89 | 166.865 | 231.615 |
| Comparing HMGCS1 expression between groups | FDR |
|---|---|
| d2 AG+ cells VS d2 BTAG+ cells | NS |
| d2 AG+ cells VS d4 AG+ cells | NS |
| d2 AG+ cells VS d4 BTAG+ cells | NS |
| d2 AG+ cells VS d6 BTAG+ cells | NS |
| d2 AG+ cells VS d6 CSM+ cells | NS |
| d2 AG+ cells VS d8 BTAG+ cells | NS |
| d2 AG+ cells VS hiPSC | 0.00658729927448284 |
| d2 AG+ cells VS iMeLC | NS |
| d2 BTAG+ cells VS d4 AG+ cells | NS |
| d2 BTAG+ cells VS d4 BTAG+ cells | NS |
| d2 BTAG+ cells VS d6 BTAG+ cells | NS |
| d2 BTAG+ cells VS d6 CSM+ cells | NS |
| d2 BTAG+ cells VS d8 BTAG+ cells | NS |
| d2 BTAG+ cells VS hiPSC | 1.14162275606314e-05 |
| d2 BTAG+ cells VS iMeLC | 0.0084512080639028 |
| d4 AG+ cells VS d4 BTAG+ cells | NS |
| d4 AG+ cells VS d6 BTAG+ cells | NS |
| d4 AG+ cells VS d6 CSM+ cells | NS |
| d4 AG+ cells VS d8 BTAG+ cells | NS |
| d4 AG+ cells VS hiPSC | 0.00710773602350321 |
Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.
KEGG GO Others d2 AG+ cells[2]
d2 BTAG+ cells[5]
d4 AG+ cells[2]
d4 BTAG+ cells[5]
d6 BTAG+ cells[4]
d6 CSM+ cells[2]
d8 BTAG+ cells[2]
hiPSC[11]
iMeLC[4]
