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Gene View

General Information

MTHFS[ENSG00000136371]

SynonymsHsT19268
Description5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Chromosome15q25.1
Database ReferenceMIM:604197 HGNC:7437 HPRD:09174 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE75140

Gene Rank

Gene Expression

 

Displaying 1-9 of 9 results.
MTHFS expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
ESC H9[53 days]0082.441
fetal human cortex 1[12 weeks post-conception]00230.19
fetal human cortex 2[13 weeks post-conception]0046.957
iPSC 409B2[33 days]00151.853
iPSC 409B2[35 days]00142.168
iPSC 409B2[37 days]00153.349
iPSC 409B2[41 days]00356.877
iPSC 409B2[58 days]00254.687
iPSC 409B2[65 days]00240.869
Displaying 1-20 of 36 results.
Comparing MTHFS expression between groupsFDR
ESC H9[53 days] VS fetal human cortex 1[12 weeks post-conception]NS
ESC H9[53 days] VS fetal human cortex 2[13 weeks post-conception]NS
ESC H9[53 days] VS iPSC 409B2[33 days]NS
ESC H9[53 days] VS iPSC 409B2[35 days]0.014890729440775
ESC H9[53 days] VS iPSC 409B2[37 days]0.00221245184782766
ESC H9[53 days] VS iPSC 409B2[41 days]0.00878251668040856
ESC H9[53 days] VS iPSC 409B2[58 days]NS
ESC H9[53 days] VS iPSC 409B2[65 days]NS
fetal human cortex 1[12 weeks post-conception] VS fetal human cortex 2[13 weeks post-conception]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[33 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[35 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[37 days]0.04883777633049
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[41 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[58 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[65 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[33 days]0.0465698738193972
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[35 days]0.0048495661444223
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[37 days]0.0010323138108089
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[41 days]0.00306231787942684
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[58 days]NS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for MTHFS

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 ESC H9[53 days][96]
 fetal human cortex 1[12 weeks post-conception][164]
 fetal human cortex 2[13 weeks post-conception][62]
 iPSC 409B2[33 days][40]
 iPSC 409B2[35 days][68]
 iPSC 409B2[37 days][71]
 iPSC 409B2[41 days][74]
 iPSC 409B2[58 days][79]
 iPSC 409B2[65 days][80]