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Gene View

General Information

MX2[ENSG00000183486]

SynonymsMXB
DescriptionMX dynamin like GTPase 2
Chromosome21q22.3
Database ReferenceMIM:147890 HGNC:7533 HPRD:01001 Vega:OTTHUMG00000086753 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
MX2 expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC007
candidate PCa CTC CSPC003,808
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)002
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)0039
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)001
PCa cell line00482
white blood cell CRPC000
white blood cell healthy1811,2328,583
Displaying 1-20 of 28 results.
Comparing MX2 expression between groupsFDR
PCa cell line VS white blood cell CRPC5.84514817665304e-07
PCa cell line VS white blood cell healthy7.87288186355877e-07
candidate PCa CTC CRPC VS PCa cell line0.000270668323493254
candidate PCa CTC CRPC VS candidate PCa CTC CSPC2.87103467290054e-07
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthy9.93981974835718e-05
candidate PCa CTC CSPC VS PCa cell line3.26578803628656e-12
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)1.28663508527569e-10
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)1.61708061607751e-05
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)0.0089493573438695
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell line0.0057502033715399
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPC0.0114815839827572
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthy3.20248198508838e-14
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for MX2

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 candidate PCa CTC CRPC[33]
 candidate PCa CTC CSPC[12]
 lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)[37]
 lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)[36]
 lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)[4]
 PCa cell line[30]
 white blood cell CRPC[2]
 white blood cell healthy[3]