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Gene View

General Information

PHGDH[ENSG00000092621]

Synonyms3-PGDH;3PGDH;HEL-S-113;NLS;NLS1;PDG;PGAD;PGD;PGDH;PHGDHD;SERA
Descriptionphosphoglycerate dehydrogenase
Chromosome1p12
Database ReferenceMIM:606879 HGNC:8923 HPRD:06047 Vega:OTTHUMG00000012100 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PHGDH expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC0011,261
candidate PCa CTC CSPC007
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)022,513
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)014.56,638
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)02,3617,169
PCa cell line11,2267,108
white blood cell CRPC00.51
white blood cell healthy000
Displaying 1-20 of 28 results.
Comparing PHGDH expression between groupsFDR
PCa cell line VS white blood cell CRPC0.00017385888502889
PCa cell line VS white blood cell healthyNS
candidate PCa CTC CRPC VS PCa cell lineNS
candidate PCa CTC CRPC VS candidate PCa CTC CSPCNS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthyNS
candidate PCa CTC CSPC VS PCa cell line3.20595748397013e-16
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)9.39033568868662e-05
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)2.28229472292272e-08
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)3.91970920733249e-05
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell line0.00070102411305983
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPCNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthyNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PHGDH

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others