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General Information

PLP1[ENSG00000123560]

SynonymsGPM6C;HLD1;MMPL;PLP;PLP/DM20;PMD;SPG2
Descriptionproteolipid protein 1
ChromosomeXq22
Database ReferenceMIM:300401 HGNC:9086 HPRD:02321 Vega:OTTHUMG00000022111 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PLP1 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell005.65
CAF0046.291
Endothelial cell0034.701
Macrophage00200.756
melanoma0293.9165,249.566
melanoma tumor001,781.718
T-cell00782.039
unresolved02.691,248.272
Displaying 1-20 of 28 results.
Comparing PLP1 expression between groupsFDR
B-cell VS CAF0.000462387657770376
B-cell VS Endothelial cell5.69485290817956e-14
B-cell VS Macrophage6.58791118889381e-13
B-cell VS T-cell6.40209690783969e-05
B-cell VS melanoma tumor3.61383367238757e-07
B-cell VS melanoma4.43448585861068e-66
B-cell VS unresolved3.25777821329885e-06
CAF VS Endothelial cellNS
CAF VS MacrophageNS
CAF VS T-cell0.00253620515300297
CAF VS melanoma tumor0.0211769330826382
CAF VS melanoma9.53315922556916e-37
CAF VS unresolved1.11647579010095e-09
Endothelial cell VS Macrophage0.020526850814053
Endothelial cell VS T-cell2.95022301760496e-12
Endothelial cell VS melanoma tumor1.02637026342279e-07
Endothelial cell VS melanoma1.1031450621849e-107
Endothelial cell VS unresolved3.33335296480075e-13
Macrophage VS T-cell2.55811209108631e-11
Macrophage VS melanoma tumor4.77590583475865e-07
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PLP1

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]