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Gene View

General Information

PRAME[ENSG00000185686]

SynonymsCT130;MAPE;OIP-4;OIP4
Descriptionpreferentially expressed antigen in melanoma
Chromosome22q11.22
Database ReferenceMIM:606021 HGNC:9336 HPRD:05820 Vega:OTTHUMG00000151172 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PRAME expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell001,158.003
CAF0026.67
Endothelial cell009.97
Macrophage00389.189
melanoma0666.2573,924.673
melanoma tumor002,516.506
T-cell001,009.063
unresolved0316.7282,286.989
Displaying 1-20 of 28 results.
Comparing PRAME expression between groupsFDR
B-cell VS CAFNS
B-cell VS Endothelial cellNS
B-cell VS MacrophageNS
B-cell VS T-cellNS
B-cell VS melanoma tumorNS
B-cell VS melanoma1.85496043591667e-34
B-cell VS unresolved0.00602918506992595
CAF VS Endothelial cellNS
CAF VS Macrophage0.0251331253880686
CAF VS T-cellNS
CAF VS melanoma tumor0.00047957997446159
CAF VS melanoma5.13229765885213e-151
CAF VS unresolved4.75291812925202e-14
Endothelial cell VS Macrophage0.00240024268027482
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumor1.57118000936247e-05
Endothelial cell VS melanoma4.64974859274638e-180
Endothelial cell VS unresolved8.86554164697413e-18
Macrophage VS T-cellNS
Macrophage VS melanoma tumorNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PRAME

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]