Loading

Gene View

General Information

PRF1[ENSG00000180644]

SynonymsFLH2;HPLH2;P1;PFN1;PFP
Descriptionperforin 1
Chromosome10q22
Database ReferenceMIM:170280 HGNC:9360 HPRD:01362 Vega:OTTHUMG00000018412 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PRF1 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell001,862.991
CAF001.22
Endothelial cell00105.53
Macrophage0012.899
melanoma00295.331
melanoma tumor0030,625.74
T-cell0010,198.11
unresolved006,186.458
Displaying 1-20 of 28 results.
Comparing PRF1 expression between groupsFDR
B-cell VS CAF0.0419449712973072
B-cell VS Endothelial cellNS
B-cell VS MacrophageNS
B-cell VS T-cell7.52036002309511e-29
B-cell VS melanoma tumor6.05354530826802e-08
B-cell VS melanoma0.00743441411401183
B-cell VS unresolvedNS
CAF VS Endothelial cellNS
CAF VS MacrophageNS
CAF VS T-cell1.74656315205745e-36
CAF VS melanoma tumor1.89888920075647e-20
CAF VS melanomaNS
CAF VS unresolved5.87371368319085e-05
Endothelial cell VS MacrophageNS
Endothelial cell VS T-cell9.86005537529124e-46
Endothelial cell VS melanoma tumor4.65987178058843e-20
Endothelial cell VS melanomaNS
Endothelial cell VS unresolved0.00197900027670061
Macrophage VS T-cell1.30477429699537e-77
Macrophage VS melanoma tumor4.28604360755709e-37
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PRF1

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]