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| Synonyms | HCP;HCPH;HPTP1C;PTP-1C;SH-PTP1;SHP-1;SHP-1L;SHP1 |
| Description | protein tyrosine phosphatase, non-receptor type 6 |
|---|---|
| Chromosome | 12p13 |
| Database Reference | MIM:176883 HGNC:9658 HPRD:01475 Vega:OTTHUMG00000168518 |
| See related | THE HUMAN PROTEIN ATLAS |
| Dataset | GSE72056 |
| PTPN6 expression in each cell group | Minimum Value (TPM) | Median Value (TPM) | Maximum Value (TPM) |
|---|---|---|---|
| B-cell | 0 | 359.898 | 3,928.22 |
| CAF | 0 | 0 | 0 |
| Endothelial cell | 0 | 0 | 67.92 |
| Macrophage | 0 | 230.293 | 2,125.011 |
| melanoma | 0 | 0 | 222.152 |
| melanoma tumor | 0 | 0 | 3,569.465 |
| T-cell | 0 | 0 | 4,265.354 |
| unresolved | 0 | 0 | 2,072.828 |
| Comparing PTPN6 expression between groups | FDR |
|---|---|
| B-cell VS CAF | NS |
| B-cell VS Endothelial cell | 2.57533022690158e-44 |
| B-cell VS Macrophage | NS |
| B-cell VS T-cell | 6.15551850281454e-09 |
| B-cell VS melanoma tumor | 0.0046486879586774 |
| B-cell VS melanoma | 5.88026939283077e-34 |
| B-cell VS unresolved | 9.81332769248357e-15 |
| CAF VS Endothelial cell | NS |
| CAF VS Macrophage | NS |
| CAF VS T-cell | NS |
| CAF VS melanoma tumor | NS |
| CAF VS melanoma | NS |
| CAF VS unresolved | NS |
| Endothelial cell VS Macrophage | 2.32354448466753e-10 |
| Endothelial cell VS T-cell | 2.35806602905269e-11 |
| Endothelial cell VS melanoma tumor | 1.10783458799954e-10 |
| Endothelial cell VS melanoma | 0.0267358865187549 |
| Endothelial cell VS unresolved | NS |
| Macrophage VS T-cell | NS |
| Macrophage VS melanoma tumor | NS |
Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.
KEGG GO Others B-cell[326]
CAF[39]
Endothelial cell[40]
Macrophage[42]
melanoma[1071]
melanoma tumor[246]
T-cell[1302]
unresolved[96]
