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Gene View

General Information

SRD5A3[ENSG00000128039]

SynonymsCDG1P;CDG1Q;KRIZI;SRD5A2L;SRD5A2L1
Descriptionsteroid 5 alpha-reductase 3
Chromosome4q12
Database ReferenceMIM:611715 HGNC:25812 HPRD:07825 Vega:OTTHUMG00000128733 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
SRD5A3 expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC003
candidate PCa CTC CSPC0030
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)0082
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)004,147
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)00.51
PCa cell line036.52,140
white blood cell CRPC000
white blood cell healthy018
Displaying 1-20 of 28 results.
Comparing SRD5A3 expression between groupsFDR
PCa cell line VS white blood cell CRPCNS
PCa cell line VS white blood cell healthy0.0129109301591439
candidate PCa CTC CRPC VS PCa cell line3.71445145874431e-15
candidate PCa CTC CRPC VS candidate PCa CTC CSPC0.0444176775718594
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)0.0222452038050743
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)8.74767134029681e-09
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthyNS
candidate PCa CTC CSPC VS PCa cell line2.02597928289825e-05
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)0.00972104794645541
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell line7.20707786779009e-05
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)0.00160717897054436
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPCNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthyNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for SRD5A3

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 candidate PCa CTC CRPC[33]
 candidate PCa CTC CSPC[12]
 lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)[37]
 lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)[36]
 lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)[4]
 PCa cell line[30]
 white blood cell CRPC[2]
 white blood cell healthy[3]