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  HepG2 cell line

Overall Design6 single human HepG2 cell line cells were sequenced using the newly developed scTrio-seq, other 2 HepG2 cells were sequenced using scRNA-seq and other 2 HepG2 cells were sequenced using scRRBS as technique control. 6 single mouse embryonic stem cells (mESCs) were sequenced using the newly developted scTrio-seq. Meanwhile, two scRNA-seq and two scRRBS were also completed using two mESCs separately. 26 single cells from hepatocellular carcinoma were sequenced using scTrio-seq to analyze the regulation relations between three omics of cancer cells.
SummarySingle cell genome, DNA methylome, and transcriptome sequencing has been achieved separately. However, to analyze the regulation of RNA expression by genetic and epigenetic factors within an individual cell, it is necessary to analyze these omics simultaneously from the same single cell. Here we developed a single cell triple omics sequencing technique- scTrio-seq, to analyze the genome, DNA methylome, and transcriptome concurrently of a mammalian cell.
Dataset viewGSE65364

Samples in HepG2 cell line

Displaying 1-8 of 8 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65364GSM2039755HiSeq X TenHomo sapiensscTrio_HepG2_1_RNAHepG2 cell line
GSE65364GSM2039757HiSeq X TenHomo sapiensscTrio_HepG2_2_RNAHepG2 cell line
GSE65364GSM2039759HiSeq X TenHomo sapiensscTrio_HepG2_3_RNAHepG2 cell line
GSE65364GSM2039761HiSeq X TenHomo sapiensscTrio_HepG2_4_RNAHepG2 cell line
GSE65364GSM2039763HiSeq X TenHomo sapiensscTrio_HepG2_5_RNAHepG2 cell line
GSE65364GSM2039765HiSeq X TenHomo sapiensscTrio_HepG2_6_RNAHepG2 cell line
GSE65364GSM2039769HiSeq X TenHomo sapiensscRNA-seq_HepG2_1HepG2 cell line
GSE65364GSM2039770HiSeq X TenHomo sapiensscRNA-seq_HepG2_2HepG2 cell line

Gene rank in HepG2 cell line

Displaying 1-10 of 15622 results.
Rank orderGene SymbolEnsembl ID