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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 1-10 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395441Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D07glioblastoma [Cla]
GSE57872GSM1395458Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E12glioblastoma [Cla]
GSE57872GSM1395476Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G06glioblastoma [Cla]
GSE57872GSM1395479Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G09glioblastoma [Cla]
GSE57872GSM1395482Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G12glioblastoma [Cla]
GSE57872GSM1395496Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A02glioblastoma [Cla]
GSE57872GSM1395526Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C08glioblastoma [Cla]
GSE57872GSM1395558Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F04glioblastoma [Cla]
GSE57872GSM1395567Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G01glioblastoma [Cla]
GSE57872GSM1395578Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G12glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5861-5870 of 5942 results.
Rank orderGene SymbolEnsembl ID
5861HTR3BENSG00000149305
5862CALB1ENSG00000104327
5863ENPP2ENSG00000136960
5864TAGLNENSG00000149591
5865SMYD2ENSG00000143499
5866SEPT4ENSG00000108387
5867USP44ENSG00000136014
5868CDH13ENSG00000140945
5869RN7SL1ENSG00000276168
5870ELTD1