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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 31-40 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395843Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F01glioblastoma [Cla]
GSE57872GSM1395845Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F03glioblastoma [Cla]
GSE57872GSM1395853Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F11glioblastoma [Cla]
GSE57872GSM1395862Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G08glioblastoma [Cla]
GSE57872GSM1395864Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G10glioblastoma [Cla]
GSE57872GSM1395865Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G11glioblastoma [Cla]
GSE57872GSM1395869Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H03glioblastoma [Cla]
GSE57872GSM1395871Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H05glioblastoma [Cla]
GSE57872GSM1395872Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H06glioblastoma [Cla]
GSE57872GSM1395874Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H08glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5891-5900 of 5942 results.
Rank orderGene SymbolEnsembl ID
5891DSC1ENSG00000134765
5892IL6ENSG00000136244
5893NELL1ENSG00000165973
5894C21orf7
5895FAM182BENSG00000175170
5896DEM1
5897ALPPENSG00000163283
5898TDGF1P3ENSG00000225366
5899EN2ENSG00000164778
5900DDIT4LENSG00000145358