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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 1-10 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395441Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D07glioblastoma [Cla]
GSE57872GSM1395458Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E12glioblastoma [Cla]
GSE57872GSM1395476Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G06glioblastoma [Cla]
GSE57872GSM1395479Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G09glioblastoma [Cla]
GSE57872GSM1395482Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G12glioblastoma [Cla]
GSE57872GSM1395496Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A02glioblastoma [Cla]
GSE57872GSM1395526Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C08glioblastoma [Cla]
GSE57872GSM1395558Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F04glioblastoma [Cla]
GSE57872GSM1395567Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G01glioblastoma [Cla]
GSE57872GSM1395578Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G12glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5901-5910 of 5942 results.
Rank orderGene SymbolEnsembl ID
5901KLK6ENSG00000167755
5902BMP5ENSG00000112175
5903DEFA1ENSG00000206047
5904CLVS1ENSG00000177182
5905ASB5ENSG00000164122
5906SLC31A2ENSG00000136867
5907NID2ENSG00000087303
5908RNASE1ENSG00000129538
5909MYO1GENSG00000136286
5910ERMNENSG00000136541