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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 31-40 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395843Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F01glioblastoma [Cla]
GSE57872GSM1395845Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F03glioblastoma [Cla]
GSE57872GSM1395853Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F11glioblastoma [Cla]
GSE57872GSM1395862Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G08glioblastoma [Cla]
GSE57872GSM1395864Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G10glioblastoma [Cla]
GSE57872GSM1395865Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G11glioblastoma [Cla]
GSE57872GSM1395869Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H03glioblastoma [Cla]
GSE57872GSM1395871Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H05glioblastoma [Cla]
GSE57872GSM1395872Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H06glioblastoma [Cla]
GSE57872GSM1395874Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H08glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 51-60 of 5942 results.
Rank orderGene SymbolEnsembl ID
51CALM1ENSG00000198668
52MATR3ENSG00000015479
53ARL6IP1ENSG00000170540
54MAGED1ENSG00000179222
55PPIAENSG00000196262
56SRIENSG00000075142
57PPP1CBENSG00000213639
58RPLP0ENSG00000089157
59HNRNPA1ENSG00000135486
60HEPN1ENSG00000221932