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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 1-10 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395591Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A01glioblastoma [Mes]
GSE57872GSM1395592Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A02glioblastoma [Mes]
GSE57872GSM1395595Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A05glioblastoma [Mes]
GSE57872GSM1395597Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A07glioblastoma [Mes]
GSE57872GSM1395598Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A08glioblastoma [Mes]
GSE57872GSM1395600Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A10glioblastoma [Mes]
GSE57872GSM1395602Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A12glioblastoma [Mes]
GSE57872GSM1395603Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B01glioblastoma [Mes]
GSE57872GSM1395605Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B03glioblastoma [Mes]
GSE57872GSM1395606Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B04glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 91-100 of 5942 results.
Rank orderGene SymbolEnsembl ID
91PJA2ENSG00000198961
92CNN3ENSG00000117519
93HNRNPA1ENSG00000135486
94SRSF6ENSG00000124193
95HSP90AA1ENSG00000080824
96SDCBPENSG00000137575
97GFAPENSG00000131095
98MAGED2ENSG00000102316
99CALM1ENSG00000198668
100EEF1GENSG00000254772