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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 1-10 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395591Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A01glioblastoma [Mes]
GSE57872GSM1395592Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A02glioblastoma [Mes]
GSE57872GSM1395595Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A05glioblastoma [Mes]
GSE57872GSM1395597Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A07glioblastoma [Mes]
GSE57872GSM1395598Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A08glioblastoma [Mes]
GSE57872GSM1395600Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A10glioblastoma [Mes]
GSE57872GSM1395602Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A12glioblastoma [Mes]
GSE57872GSM1395603Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B01glioblastoma [Mes]
GSE57872GSM1395605Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B03glioblastoma [Mes]
GSE57872GSM1395606Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B04glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 101-110 of 5942 results.
Rank orderGene SymbolEnsembl ID
101MIR3652
102ATP5A1ENSG00000152234
103PGK1ENSG00000102144
104RPL7ENSG00000147604
105LGALS3BPENSG00000108679
106NEAT1ENSG00000245532
107CAPZA2ENSG00000198898
108C1RENSG00000159403
109SERINC1ENSG00000111897
110PPP2R1AENSG00000105568